Puppers perished at the age of 32, three years after being diagnosed with motor neuron disease (MND).
The US Twitch broadcaster rose to prominence while playing the survival game Dead by Daylight, where he was known for his upbeat demeanor.
Following his diagnosis, the gaming community coalesced around him and established the Light in the Fog Foundation, raising $270,000 (£216,500) to support his care.
In reference to his catchphrase, the foundation stated that Puppers would be “forever in our hearts, forever comfortable.”
Puppers, also known as Max, would tell his viewers, “Stay comfortable, because if you’re comfortable, you’re winning.”
In 2020, the streamer was diagnosed with ALS, the most prevalent form of MND.
According to the NHS, it affects the brain and nerves and causes paralysis that worsens over time. There is no cure for the disease, but there are treatments that can help reduce its daily impact.
A tweet confirming his passing stated that he “loved you all so very much.”
“Thank you for all of your love and support throughout his career – making you all happy was truly what he lived for,” the note read.
A source of positivity
When Max was diagnosed with ALS, his online companions Eshleee, Sunshine, and Silver “moved across the country” to provide him with care and support.
“Being his caregiver while he battled this dreadful disease was the greatest challenge and greatest joy of my life,” Sunshine told the BBC.
“I will never forget him, and a piece of my heart will remain empty without him.”
Silver stated that they will “never forget” Max’s chuckle and playing Dead by Daylight alongside him, and Eshleee referred to the streamer as a “beacon of positivity.”
“I can’t think of a single person who has had a greater impact on my life or the lives of so many,” they said.
The last two years I’ve spent with him have been invaluable.
Max’s diagnosis “devastated” the three, who founded Light in the Fog to assist others.
More than 150 Dead by Daylight broadcasters participated in a multi-day event to raise funds for his treatment and care, which was bolstered by endorsements from MrBeast, the YouTuber with the most subscribers.
The group is now requesting additional funds from the community to help cover his funeral expenses and unpaid medical bills from his treatment.
There has been an outpouring of support from the gaming community, who have referred to him as a “true gaming champion” and “a kind soul we didn’t deserve.”
The developers of Dead by Daylight, who had previously added a commemorative item to the game in his honor, referred to him as “one of the brightest lights in The Fog,” a feature that allows players to remain concealed from one another.
Hundreds of admirer responses to the news contained Puppers’ signature sign-off. “Relax,” many of the posts stated, “stay comfortable.”