The 38-year-old has won 16 singles titles and a career-high world ranking of seventh in 2018. He has served a remarkable 14,411 aces.

In 2010, he played in the longest tennis match in history, defeating Nicolas Mahut 6-4 3-6 6-7 7-6 70-68 after 11 hours and five minutes.

“After 17 years on the ATP Tour, it’s time to say goodbye to professional tennis,” Isner explained.

“This transition will be difficult, but I’m looking forward to every minute of it with my incredible family.”

“My final event will be the US Open.” It’s time to put them on one more time.”

During his three-day epic with France’s Mahut in 2010, Isner served a record 113 aces and finished with a 138-game fifth set.

His highest Grand Slam result was again at the All England Club, as he reached the semi-finals in 2018 before being defeated by Kevin Anderson.

Between 2012 and 2020, Isner was the best-ranked American man in the year-end rankings, and he finished in the top 20 for a decade beginning in 2010.

The US Open draw will take place on Thursday, August 24, with the first round beginning on Monday.