Copenhagen, the Danish champions, advanced to the knockout stage for the first time since 2011. They finished ahead of Manchester United in their group.
The dates of the first two legs are February 13–14 or February 20–21, and March 5–6 or March 12–13.
Due to their seeds, City and Arsenal will host the second leg of the match at home.
The 14-time champion Real Madrid takes on RB Leipzig, Inter Milan, who finished second in the previous campaign, plays Atletico Madrid, and Bayern Munich takes on Lazio.
On June 1, the final will take place at Wembley.
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Arsenal vs. Porto in the Round of 16
Barcelona versus Napoli
Real Sociedad against Paris St. Germain
Juventus vs. Real Madrid
Eindhoven PSV vs. Dortmund Borussia
Milan versus Bayern Munich
Manchester City versus Copenhagen
Real Madrid vs. RB Leipzig
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The previous time these teams faced off, in 2010, at Emirates Stadium, Porto was defeated 5-0 by Premier League leaders Arsenal, who won Group B but have never won the Champion League.
Last season’s runners-up in Portugal’s Primeira Liga, Porto tied Barcelona for first place in Group H after winning four of their six games.
City emerged victorious in Group G with a perfect record, while Copenhagen finished second to Bayern in Group A after losing 1-0 away to United before defeating them 4-3 at home.
Over the previous six seasons, City has advanced from the last 16.
Examination
Ian Dennis, senior football correspondent for BBC Radio 5 Live
Both of the English teams should be really thrilled with the draw, which has been very kind to them.
Despite never winning at the Estadio do Dragao, Arsenal has defeated Porto in their three prior meetings.
In the previous season’s group stage matchup between City and Danish champions Copenhagen, the home team triumphed 5-0 despite drawing 0-0 away from Denmark.
Europa League playoff drawing
On Monday, there was also a play-off draw for the Europa League knockout phase.
West Ham, Brighton, Rangers, and Liverpool are among the eight group winners who automatically advance to the last-16 stage, which will take place on March 7 and 14, therefore there was little interest from the British side.
The eight teams that finished third in the Champions League group stage and the eight runners-up from the Europa League group stage will face off to determine who will advance to the play-offs.
The dates of these matches are February 15 and 22.
Roma vs. Feyenoord
Freiburg v. Lens
